ABSTRACT The manufacturing process for biological products is complex, expensive and critical to the final product, with an impact on their efficacy and safety.They have been increasingly used to treat several diseases, and account for approximately 50% of the yearly budget for the Brazilian public health system.As the patents of biological product
Abstract Background Angiotensin-converting enzyme inhibitors (ACEI) are the most common cause of drug-induced angioedema in the United States.Our primary objective was to provide descriptive evidence regarding emergency department (ED) disposition of ACEI-induced angioedema patients.Our secondary objective was to evaluate unique patterns in those w
Background and Objectives: Irritable bowel syndrome (IBS) is a chronic intestinal disorder, which is characterized by irritating pain during defecation or alteration of the bowel habits.In the curent study, the association of dietary glycemic index (GI) and glycemic load (GL) with the risk of this syndrome, was investigated in a large population of
Different lubrication methods such teucrium cossonii majoricum as oil dip or injection lubrication are used in gearboxes to lubricate tribological contacts and to dissipate frictional heat.To improve resource and energy efficiency, novel needs-based lubrication methods like the drop-on-demand lubrication are being developed.It includes an ink-jet n
Antibiotic resistance is a severe global problem afflicting the field of public 2334-080 health in recent years.Antibiotic-resistant bacteria (ARB) and their antibiotic resistance genes (ARGs) can spread into the environment via various sources like hospital wastewater, domestic wastewater, agricultural runoff, and animal feeding operations.However